When Will the Second Global Freeze Happen?

Among the objects left by Roidmude 066 was a map that hints at a second Global Freeze. The Special Investigation Unit receives an investigation request from the newly created SSDC and starts to move. Meanwhile, Gold Drive is searching for Brain to advance his plans for a new Global Freeze. Once Gold Drive, Medic, Heart and Brain are together, the Global Freeze will become a reality. However, another unthinkable character is after Brain.